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Mechanistic Analysis ofS-(1,2-Dichlorovinyl)-l-cysteine-Induced Cataractogenesisin Vitro

โœ Scribed by Colleen M.Walsh Clang; Michael D. Aleo


Book ID
112266497
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
303 KB
Volume
146
Category
Article
ISSN
0041-008X

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Chronic toxicity of S-(trans-1,2-dichlor
โœ Deborah R. Jaffe; A. Jay Gandolfi; Raymond B. Nagle ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 694 KB

S-(trans-l,2-Dichlorovinyl)-~-cysteine (DCVC) exposure causes acute renal tubular cytotoxicity. To further characterize the effects of DCVC, a chronic study was undertaken. Male Swiss-Webster mice received DCVC dissolved in their drinking water at 0.01, 0.05 and 0.1 mg ml-'. At 4, 8, 21 and 37 weeks