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Mechanisms of viral induced caspase activation in human hepatoma cell lines

✍ Scribed by Bitzer, Michael; Prinz, Florian; Wybranietz, Wolfgang; Ungerechts, Guy; Hoffmann, Alexandra; Spiegel, Martin; Gregor, Michael; Lauer, Ulrich M.

Book ID
122407684
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
187 KB
Volume
118
Category
Article
ISSN
0016-5085

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## Abstract ## Background The caspase‐3 gene is expressed at significantly lower levels in human hepatocellular carcinomas than in normal hepatocytes. Gene transfer technologies offer the possibility to restore caspase‐3 gene expression. We explored the interest for cancer gene therapy of a consti