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Mechanisms of Toxic Effect of Streptozotocin on β-Cells in the Islets of Langerhans

✍ Scribed by V. B. Pisarev; G. L. Snigur; A. A. Spasov; M. P. Samokhina; A. E. Bulanov


Publisher
Springer US
Year
2009
Tongue
English
Weight
457 KB
Volume
148
Category
Article
ISSN
0007-4888

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## Abstract Our objective was to study the effects of three (30, 40, and 50 mg/kg) doses of Streptozotocin (STZ) on fasting plasma glucose level (FPG) and observe its effects at the cellular level in rat pancreas by electron microscopy. FPG was measured in rats before induction of diabetes and then