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Mechanisms of tau-induced neurodegeneration

✍ Scribed by Khalid Iqbal; Fei Liu; Cheng-Xin Gong; Alejandra del C. Alonso; Inge Grundke-Iqbal

Book ID
106073766
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
478 KB
Volume
118
Category
Article
ISSN
0001-6322

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## Abstract Both Alzheimer's disease (AD) and almost every second case of frontotemporal lobar degeneration (FTLD) are characterized by the deposition of hyperphosphorylated forms of the microtubule‐associated protein tau in neurons and/or glia. This unifying pathology led to coining the umbrella t