𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tau Phosphorylation and Cleavage in Ethanol-Induced Neurodegeneration in the Developing Mouse Brain

✍ Scribed by Mariko Saito; Goutam Chakraborty; Rui-Fen Mao; Sun-Mee Paik; Csaba Vadasz; Mitsuo Saito


Publisher
Springer
Year
2010
Tongue
English
Weight
606 KB
Volume
35
Category
Article
ISSN
0364-3190

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Proteomics analysis of the neurodegenera
✍ Kelly Tilleman; Chris Van den Haute; Hugo Geerts; Fred van Leuven; Eddy L. Esman πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 125 KB πŸ‘ 1 views

Protein tau, a major microtubule-binding protein in the brain, comprises six isoforms generated through alternative mRNA splicing. A dysfunctional form of mutant and normal tau is associated or implicated in the pathogenesis of several neurodegenerative disorders. The neuropathological hallmark of t

The development potential of ethanol-ind
✍ Kaufman, M. H. ;Bain, I. M. πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 626 KB

## Abstract The development potential of fertilized embryos isolated from female mice previously given a single dose of either a dilute solution of ethanol or distilled water (controls) by mouth was studied. Exposure to ethanol occurred at various times during the cycle leading to ovulation and sho

Tyrosine phosphorylation of glycoprotein
✍ J. Soulliere; N. Bissoon; M. Khurgel; J. W. Gurd πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 917 KB

## Abstract The tyrosine phosphorylation of glycoproteins in the adult and developing rat brain was investigated. Immunoblotting with anti‐tyr(P) antibodies identified a glycoprotein with an apparent Mr of 180,000 (GP180) as the major tyrosine‐phosphorylated protein in the concanavalin A (con A)‐bi

Effects of cyclin-dependent kinase-5 act
✍ Shirley B. Shelton; Pavan Krishnamurthy; Gail V.W. Johnson πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 392 KB

## Abstract Cyclin‐dependent kinase‐5 (CDK5), a unique CDK family member, is active primarily in the central nervous system (CNS). Previous studies suggest that CDK5 is proapoptotic and contributes to tau hyperphosphorylation and neurodegeneration in Alzheimer's disease. The objective of this study