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Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes

✍ Scribed by Heidari, Reza; Babaei, Hossein; Eghbal, Mohammad


Book ID
121689049
Publisher
Informa plc
Year
2012
Tongue
English
Weight
641 KB
Volume
36
Category
Article
ISSN
0148-0545

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✍ Akram Jamshidzadeh; Hossein Niknahad; Hamed Kashafi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 107 KB

## Abstract Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was to investigate the cy