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Molecular mechanisms of chloroacetaldehyde-induced cytotoxicity in isolated rat hepatocytes

✍ Scribed by Christian Sood; Peter J. O'Brien

Book ID
115783370
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
677 KB
Volume
46
Category
Article
ISSN
0006-2952

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Cytotoxicity of chloroquine in isolated
Cytotoxicity of chloroquine in isolated rat hepatocytes
✍ Akram Jamshidzadeh; Hossein Niknahad; Hamed Kashafi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 107 KB

## Abstract Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was to investigate the cy