𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mechanisms of isotype determination during immunoglobulin class switch recombination in human B-cells

✍ Scribed by Fear, D.J.; McCloskey, N.; Felsenfeld, G.; Gould, H.


Book ID
119275824
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
30 KB
Volume
115
Category
Article
ISSN
1097-6825

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Enhanced intra-switch region recombinati
✍ Bernardo Reina-San-Martin; Junjie Chen; André Nussenzweig; Michel C. Nussenzweig 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

## Abstract Immunoglobulin class switch recombination (CSR) is initiated by activation‐induced cytidine deaminase (AID), an enzyme that deaminates cytidine residues in single‐stranded DNA. U:G mismatches created by AID are processed to produce lesions that recruit and activate DNA damage response p

NF-κB binds to the immunoglobulin Sγ3 re
✍ Lili Wang; Robert Wuerffel; Amy L. Kenter 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 288 KB

## Abstract Ig class switch recombination (CSR) is dependent upon the expression of activation‐induced deaminase and targeted to specific isotypes by germ‐line transcript expression and isotype‐specific factors. NF‐κB plays critical roles in multiple aspects of B cell biology and has been implicate