Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases
β Scribed by Buckner, Jane Hoyt
- Book ID
- 109956426
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 431 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1474-1741
- DOI
- 10.1038/nri2889
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## Abstract ## Background The purpose of this study was to investigate the presence of CD4^+^CD25^+^FOXP3^+^ regulatory T (Treg) cells both in peripheral blood and local tumors in patients with nasal inverted papilloma (NIP). ## Methods By using flow cytometry, the frequencies of CD4^+^CD25^+^FO
## Abstract Interleukinβ2 (ILβ2) treatment is currently used to enhance T cellβmediated immune responses against tumors or in viral infections. At the same time, ILβ2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that ILβ2 is a