Pharmacokinetics of parenteral 13-cis-re
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H. J. Guchelaar; S. Wouda; G. J. J. Beukeveld; N. H. Mulder; J. W. Oosterhuis
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Article
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1992
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John Wiley and Sons
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English
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The pharmacokinetics of three 13-cis-retinoic acid formulations were studied after intraperitoneal (ip) administration to rats. Rats were given ip injections of 2.5 mg of 13-cis-retinoic acid per 360 g of body weight; the drug was administered as an alkaline solution, suspended in corn oil, or as a