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Mechanisms of immunosuppression by 13-CIS retinoic acid in rat spleen cells

โœ Scribed by B. Gran; M. Vergelli; T. Olsson; B. Mazzanti; C. Ballerini; L. Amaducci; L. Massacesi


Book ID
119108972
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
144 KB
Volume
54
Category
Article
ISSN
0165-5728

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The pharmacokinetics of three 13-cis-retinoic acid formulations were studied after intraperitoneal (ip) administration to rats. Rats were given ip injections of 2.5 mg of 13-cis-retinoic acid per 360 g of body weight; the drug was administered as an alkaline solution, suspended in corn oil, or as a