Mechanisms of Hydrolysis and Rearrangements of Epoxides
โ Scribed by Dale L. Whalen
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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Kinetic resolution of 2-mono-and 2,2-disubstituted epoxides was accomplished using epoxide hydrolases from bacterial and fungal origin by employing lyophilized whole microbial cells. In all cases investigated, the biocatalytic hydrolysis was shown to proceed with retention of configuration at the st
The 8,14 8-epoxide of methyl sandaracopimarate undergoes new rearrangements on contact with active alumina, yielding labdane and another compound having the cycloisopimarane skeleton. In an earlier paper' dealing with the reactivity of methyl sandaracopimarate 8,14 8 epoxide l\_ towards boron triflu