Experiments were performed to compare the mechanism of block of voltage-dependent K channels by various short and long alkyl chain tetraalkylammonium (TAA) ions at internal and external sites. Current through single channels was recorded from excised membrane patches of cultured neuroblastoma cells
Mechanisms of facilitation and blocking in gramicidin channels by impermeant ions
β Scribed by Krister Bokvist; John Sandblom
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 984 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0376-7388
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract It has been shown previously that sera of tumorβbearing individuals are capable of blocking specifically the lymphocyte cytotoxicity in vitro against the tumor cells in question. The present investigation demonstrates that blocking material, in the form of sera of rats carrying progress
Voltage clamp experiments were done on single myelinated frog nerve fibres. The rate of block of Na + channels by tetrodotoxin (TTX) was obtained from changes in peak Na + current during 1-Hz trains of depolarizing impulses. In hypertonic Na+-rich solution (216 raM) the stationary block was reduced