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Mechanisms of enhanced prevalence of asthma and atopy in developed countries

✍ Scribed by JM Hopkin

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
526 KB
Volume
9
Category
Article
ISSN
0952-7915

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✦ Synopsis

Atopy-a T helper 2 cell driven hypersensitivity to innocuous antigens (allergens) which causes most cases of asthmais of complex genetic and environmental origins. There is compelling epidemiological evidence for a rise in atopic disease in 'westernised' communities. The changing pattern of microbial exposure in early childhood is suggested to be the principal candidate mechanism for this rise.

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