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Mechanisms of DNA damage and insight into mutations by chromium(VI) in the presence of glutathione

โœ Scribed by Paula A. Mazzer; Leila Maurmann; Rathindra N. Bose


Book ID
108174973
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
702 KB
Volume
101
Category
Article
ISSN
0162-0134

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Induction of mutagenic DNA damage by chr
โœ Shaojun Liu; Kathleen Dixon ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 824 KB

Certain chromium (Cr) compounds are known to be carcinogenic in humans and mutagenic in cell culture. However, the mechanism of Cr mutagenesis is not well understood. It appears that intracellular reduction of Cr by agents such as glutathione plays a role in the induction of DNA damage. We have used