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Mechanisms of bisphosphonate induced apoptosis in prostate cancer

✍ Scribed by Grenville Oades; Siddhika Senaratne; Ian Clarke; Roger Kirby; Kay Colston

Book ID: 118643992
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 182 KB
Volume: 1
Category: Article
ISSN: 1569-9056
DOI: 10.1016/s1569-9056(02)80614-5

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## Abstract Prostate cancer is associated with the inability of prostatic epithelial cells to undergo apoptosis rather than with increased cell proliferation. Prostate apoptosis response‐4 (Par‐4) is a unique pro‐apoptotic molecule that is capable of selectively inducing apoptosis in cancer cells w