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Mechanisms of Action of Ladasten: Activation of Gene Expression for Neurotrophins and Mitogen-Activated Kinases

✍ Scribed by M. Kh. Salimgareeva; R. S. Yamidanov; Yu. V. Vakhitova; S. B. Seredenin

Book ID
106359241
Publisher
Springer US
Year
2012
Tongue
English
Weight
450 KB
Volume
152
Category
Article
ISSN
0007-4888

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✍ Shivanand P. Lad; Kenneth E. Neet πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 515 KB

## Abstract Neurotrophins interact with two distinct classes of cell‐surface receptors, the Trk receptor tyrosine kinase family and the common neurotrophin receptor p75^NTR^. For many years, the biological role of p75^NTR^ remained obscure, being relegated to modulating Trk binding of neurotrophins