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Mechanisms of action and resistance to all-transretinoic acid (ATRA) and arsenic trioxide (As2O3) in acute promyelocytic leukemia

✍ Scribed by Tomita, Akihiro; Kiyoi, Hitoshi; Naoe, Tomoki


Book ID
120380197
Publisher
Carden Jennings Publishing
Year
2013
Tongue
English
Weight
535 KB
Volume
97
Category
Article
ISSN
0925-5710

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ALL-TRANS RETINOIC ACID (ATRA) IN THE TR
✍ C. S. CHIM; Y. L. KWONG; R. LIANG; Y. C. CHU; C. H. CHAN; L. C. CHAN; K. F. WONG πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 498 KB πŸ‘ 2 views

Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,