𝔖 Bobbio Scriptorium
✦   LIBER   ✦

All-trans retinoic acid and arsenic trioxide resistance of acute promyelocytic leukemia with the variant STAT5B-RARA fusion gene

✍ Scribed by Strehl, S; König, M; Boztug, H; Cooper, B W; Suzukawa, K; Zhang, S-J; Chen, H-Y; Attarbaschi, A; Dworzak, M N


Book ID
126688696
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
604 KB
Volume
27
Category
Article
ISSN
0887-6924

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


In vitro response to all-trans retinoic
✍ Marie-Joëlle Mozziconacci; Concetta Liberatore; Véronique Brunel; Francesco Grig 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 941 KB

Acute promyelocytic leukemia (APL) is characterized by the t(15;17) cytogenetic abnormality leading to the expression of two fusion genes, PML/RARA and RARA/PML, and by its sensitivity to all-trans retinoic acid (ATRA) differentiating treatment. Rare APL cases lacking the t(15;17) have been describe