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Mechanisms involved in suppression of ADAMTS4 expression in synoviocytes by high molecular weight hyaluronic acid

✍ Scribed by Kataoka, Yoshihiro; Ariyoshi, Wataru; Okinaga, Toshinori; Kaneuji, Takeshi; Mitsugi, Sho; Takahashi, Tetsu; Nishihara, Tatsuji


Book ID
122027598
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
679 KB
Volume
432
Category
Article
ISSN
0006-291X

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## Abstract ## Objective To examine in vivo the effects of a mixture of high molecular weight hyaluronic acid (HA) plus phospholipids on joint lubrication and articular cartilage degeneration. ## Methods Experimental osteoarthritis (OA) of the right knee was induced by anterior cruciate and medi