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Mechanisms involved in suppression of NGF-induced neuronal differentiation of PC12 cells by hyaluronic acid

โœ Scribed by Ayako Washio; Chiaki Kitamura; Eijiro Jimi; Masamichi Terashita; Tatsuji Nishihara

Book ID
113955914
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
951 KB
Volume
315
Category
Article
ISSN
0014-4827

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## Abstract In vivo, the neurotoxin MPTP is oxidated to MPP^+^, which is toxic to dopaminergic neurons. In this paper, we have used MPP^+^ as a tool to evoke neurotoxicity in the PC12 cell line and investigate the intracellular events that are involved. A cytotoxicity test, performed on undifferent