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Mechanisms in Muscle Atrophy in Immobilization and Aging

✍ Scribed by MARINA BAR-SHAI; ELI CARMELI; RAYMOND COLEMAN; ABRAHAM Z. REZNICK

Book ID
111478189
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
709 KB
Volume
1019
Category
Article
ISSN
0890-6564

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## Abstract We describe a new cast‐immobilization protocol to induce muscle atrophy in the lower hindlimb muscles of mice. Bilateral cast immobilization for 2 weeks in a shortened position resulted in a significant loss of muscle size and strength in the soleus and extensor digitorum longus. The av