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Mechanisms and clinical implications of thrombosis in paroxysmal nocturnal hemoglobinuria

โœ Scribed by S. T. A. VAN BIJNEN; W. L. VAN HEERDE; P. MUUS


Book ID
109154967
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
215 KB
Volume
10
Category
Article
ISSN
1538-7933

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Mechanism of intravascular hemolysis in
โœ Nakakuma, Hideki ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 832 KB

Paroxysmal nocturnal hemoglobinuria (PNH) hemolysis requires both intravascular complement activation and affected erythrocytes susceptible to complement. This susceptibility is explained by a deficiency in complement regulatory membrane proteins that are attached to the membrane by a glycosylphosph