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Mechanism of Thyroxine Formation from Diiodotyrosine and p-Hydroxydiiodophenylpyruvic Acid

โœ Scribed by F. Blasi; F. Fragomele; I. Covelli


Book ID
115111678
Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
663 KB
Volume
5
Category
Article
ISSN
1432-1327

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Kinetics and mechanism of oxime formatio
โœ A. Malpica; M. Calzadilla; T. Cordova ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 61 KB ๐Ÿ‘ 2 views

The following lines of evidence establish that oxime formation from pyruvic acid occurs with ratedetermining carbinolamine dehydration under acidic and neutral conditions. First, saturation effects observed at pH 7 are strongly suggestive of carbinolamine accumulation, requiring that dehydration of