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Mechanism of the Thermal Conversion of 3,3′-Bicyclo-propenyls into Benzene Derivatives

✍ Scribed by James H. Davis; Prof. Dr. Kenneth J. Shea; Prof. Robert G. Bergman


Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
343 KB
Volume
15
Category
Article
ISSN
0044-8249

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## Abstract magnified image A simple one pot synthetic method for the isomerization of cephem double bond from the natural 3‐position to 2‐cephem positions is affected by silylation. Thus cephalosporin acids are treated with Ntrimethylsilylacetamide (MSA) or __N,O__‐bis(trimethylsilyl)acetamide (B