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Mechanism of the impairment of the glucagon-stimulated phosphoenolpyruvate carboxykinase gene expression by interleukin-6 in rat hepatocytes: Inhibition of the increase in cyclic 3',5' adenosine monophosphate and the downstream cyclic 3',5' adenosine monophosphate action

✍ Scribed by B Christ; A Nath; K Jungermann


Book ID
118686644
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
265 KB
Volume
26
Category
Article
ISSN
0270-9139

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Mechanism of the impairment of the gluca
✍ B Christ; A Nath; K Jungermann πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 262 KB

ferase reporter gene construct under the control of a PCK In cultured rat hepatocytes, the gluconeogenic key enzyme, phosphoenolpyruvate carboxykinase (PCK), is induced by gene promoter fragment (base 0979 to base /32). Luciferase activity was determined after stimulation of the cells with glucagon