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Mechanism of the hydrolysis of chloroazines to hydrazides and cyclization to oxadiazoles.

✍ Scribed by P.A. Cashell; A.F. Hegarty; F.L. Scott

Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
235 KB
Volume
12
Category
Article
ISSN
0040-4039

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✦ Synopsis

Both 1-chloro (

and

1,4-dichloro)-1,4-diaryl-2,3-diaza-1,3-butadienes (1

and

2

) have been used extensively as starting materials in heterocyclic s&thesTs.' The first step in these reactions generally involves displacement of one or both chlorine atoms. Despite the analogy with acyl chlorideg3 nucleophilic substitution at the aza systems ,& and ,2 has not been studied in detail.

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