𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations

✍ Scribed by Nikolova, P. V.


Book ID
111747735
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
419 KB
Volume
19
Category
Article
ISSN
0261-4189

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The screening of the second-site suppres
✍ Kazunori Otsuka; Shunsuke Kato; Yuichi Kakudo; Satsuki Mashiko; Hiroyuki Shibata πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 372 KB

## Abstract Second‐site suppressor (SSS) mutations in p53 found by random mutagenesis have shown to restore the inactivated function of some tumor‐derived p53. To screen novel SSS mutations against common mutant p53s, intragenic second‐site (SS) mutations were introduced into mutant p53 cDNA in a c