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Mechanism of inhibition of ribonucleoside diphosphate reductase by ga-(n)-heterocyclic aldehyde thiosemicarbazones

โœ Scribed by Alan C. Sartorelli; Krishna C. Agrawal; E.Colleen Moore


Book ID
115770728
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
390 KB
Volume
20
Category
Article
ISSN
0006-2952

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## Abstract 2โ€ฒโ€Azidoโ€2โ€ฒโ€deoxyribonucleoside 5โ€ฒโ€diphosphates are mechanismโ€based inhibitors of Ribonucleotide Reductase. Considerable effort has been made to elucidate their mechanism of inhibition, which is still controversial and not fully understood. Previous studies have detected the formation o