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Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa

โœ Scribed by Joen-Rong Sheu; Wei-Chun Hung; Yen-Mei Lee; Mao-Hsiung Yen


Book ID
117098934
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
654 KB
Volume
318
Category
Article
ISSN
0014-2999

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A biologically monitored fractionation of methanol extracts of the fruit of Evodia rutaecarpa led to the isolation of quinolone alkaloids, evocarpin (1), 1-methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone (2) and 1-methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone (3) as blockers of angiote