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Mechanism of Inhibition of Bacillus subtilis DNA Polymerase III by the Arylhydrazinopyrimidine Antimicrobial Agents

✍ Scribed by Robert L. Low, Stephan A. Rashbaum and Nicholas R. Cozzarelli


Book ID
123652112
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
947 KB
Volume
71
Category
Article
ISSN
0027-8424

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Mapping of the gene specifying DNA polym
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polC, the gene specifying the structure of the replication-specific DNA polymerase III of B. subtilis, was mapped by exploiting azp-12, a mutation conferring resistance to azopyrimidine which determines a mutant, azopyrimidine-resistant enzyme. azp-12 was located in the area of the pyrA locus and is