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Mechanism of increased renal prostaglandin E2 in uranyl nitrate-induced acute renal failure

✍ Scribed by Anshumali Chaudhari; Michael A. Kirschenbaum

Book ID
119049494
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
629 KB
Volume
26
Category
Article
ISSN
0090-6980

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## Abstract In rats pretreated with dexamethasone (an inducer of CYP3A1/2 in rats) and troleandomycin (an inhibitor of CYP3A1/2 in rats), the area under the plasma concentration–time curve from time zero to time infinity (__AUC__) values of clarithromycin were significantly smaller (365 compared wi