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Mechanism of human placental aromatase: A new active site model

✍ Scribed by Oh, Soonsin S.; Robinson, Cecil H.


Book ID
121671635
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
615 KB
Volume
44
Category
Article
ISSN
0960-0760

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ChemInform Abstract: Evidence for New No
✍ P. AUVRAY; S. MOSLEMI; P. SOURDAINE; S. GALOPIN; G.-E. SERALINI; C. ENGUEHARD; P πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 2 views

Site. -Depending on the reaction time, indan-1-ones (III) and inden-1-ones (V) are prepared. They are further used to study the active binding site of human aromatase inhibitors. Two compounds (Vb) and (Vc) are good inhibitors of human aromatase whereas they weakly inhibit the equine enzyme.