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Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells

โœ Scribed by Kim, Sung Phil; Kang, Mi Young; Choi, Yong Hee; Kim, Jae Ho; Nam, Seok Hyun; Friedman, Mendel

Book ID
120845743
Publisher
The Royal Society of Chemistry
Year
2011
Tongue
English
Weight
519 KB
Volume
2
Category
Article
ISSN
2042-6496

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Tumor necrosis factor-a (TNF-a) is a cytokine that induces apoptosis in various cell systems by binding to the TNF receptor (TNFR). To study TNF-a-induced apoptosis, we isolated and characterized a novel TNF-a-resistant variant, U937/ TNF clone UA, from human monocytic leukemia U937 cells. The UA ce