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Mechanism of enhanced vasoconstrictor hormone action in vascular smooth muscle cells by cyclosporin A

✍ Scribed by Alexandre Lo Russo; Anne-Catherine Passaquin; Urs T Rüegg


Book ID
110002893
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
324 KB
Volume
121
Category
Article
ISSN
0007-1188

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Pretreatment of rat vascular smooth muscle cells with cyclosporin A caused concentration- and time-dependent enhancement of both angiotensin II- and platelet-derived growth factor-stimulated cellular functions, which may be related to a rise in vascular tone. In particular, cyclosporin A increased c