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Cyclosporine A enhances total cell calcium independent of Na-ATPase in vascular smooth muscle cells

โœ Scribed by Bokemeyer, D. ;Friedrichs, U. ;Backer, A. ;Kramer, H. J. ;Meyer-Lehnert, H.

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
416 KB
Volume
72
Category
Article
ISSN
1432-1440

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Using the single electrode voltage-clamp technique, vascular smooth muscle cells from the guinea pig portal vein showed an initial inward (Ca2+) current followed by an outward current which peaked within 100 ms and then declined to a steady level in a few seconds. Caffeine (1 mmol/l) selectively blo