Mechanism of drug release from an acrylic polymer-wax matrix tablet
β Scribed by Hua-Pin Huang; Surendra C. Mehta; Galen W. Radebaugh; Mahdi B. Fawzi
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 382 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
## Abstract A previously derived cubic equation describing the release of drugs from matrix tablets is compared with a more complex equation recently presented. Using data obtained from cylindrical hydrocortisone matrix tablets, it is shown that the simpler cubic equation affords an equally accepta
The aim of this study was to determine, whether interactions between a drug and hydrophobic polymer matrix are present, and if so, how they affect the drug release. In addition, the most important formulation parameters, for example porosity or structure of the tablet, which have the greatest impact