Drug release from methyl acrylate-methyl methacrylate copolymer matrix I: Kinetics of release
โ Scribed by B. Farhadieh; S. Borodkin; J. D. Buddenhagen
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 457 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Polymer-containing tablet preparation was studied using radiation-induced polymerization of glass-forming monomers at low temperatures in the presence of dimethylaminoethyl methacrylate-methyl methacrylate copolymer or methyl acrylate-methacrylic acid copolymer. Drug dissolution from tablets was in
Weakly basic drugs and their salts exhibit a drop in aqueous solubility at high pH conditions, which can result in low and incomplete release of these drugs from sustained release formulations. The objective of this study is to modulate matrix microenvironmental pH by incorporation of acidic polymer