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Mechanism of calcium gating in small-conductance calcium-activated potassium channels

โœ Scribed by Keen, J. E.; Adelman, J. P.; Xia, X.-M.; Fakler, B.; Rivard, A.; Wayman, G.; Johnson-Pais, T.; Ishii, T.; Hirschberg, B.; Bond, C. T.; Lutsenko, S.; Maylie, J.


Book ID
109705140
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
723 KB
Volume
395
Category
Article
ISSN
0028-0836

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Skeletal muscle becomes hyperexcitable following denervation and when cultured in the absence of nerve cells. In these circumstances, the bee venom peptide toxin apamin, a blocker of small-conductance calcium-activated potassium (SK) channels, dramatically reduces the hyperexcitability. In this repo