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Bicuculline block of small-conductance calcium-activated potassium channels

โœ Scribed by Radwan Khawaled; Andrew Bruening-Wright; John P. Adelman; J. Maylie


Publisher
Springer
Year
1999
Tongue
English
Weight
146 KB
Volume
438
Category
Article
ISSN
0031-6768

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โœ David Pribnow; Teresa Johnson-Pais; Chris T. Bond; John Keen; Robert A. Johnson; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 336 KB

Skeletal muscle becomes hyperexcitable following denervation and when cultured in the absence of nerve cells. In these circumstances, the bee venom peptide toxin apamin, a blocker of small-conductance calcium-activated potassium (SK) channels, dramatically reduces the hyperexcitability. In this repo