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Mechanism of .beta.-lactam ring opening in cephalosporins

✍ Scribed by Page, Michael I.; Proctor, Philip


Book ID
126903028
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
646 KB
Volume
106
Category
Article
ISSN
0002-7863

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## Abstract The synthesis of poly(__Ξ²__‐alanine) by __Candida antarctica__ lipase B immobilized as novozyme 435 catalyzed ring‐opening of 2‐azetidinone is reported. After removal of cyclic side products and low molecular weight species pure linear poly(__Ξ²__‐alanine) is obtained. The formation of t