Mechanism of Aromatic Hydrocarbon Acylation by Substituted Benzoic Acids: A Novel Reaction Pathway
โ Scribed by P. E. Allegretti; R. D. Bravo; J. J. P. Furlong
- Book ID
- 110409648
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 105 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0023-1584
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๐ SIMILAR VOLUMES
Methylenecyclopropanes (MCPs) can react with aromatic amines to give the corresponding homoallylic amines in good to high yields in the presence of Lewis acids. The substituents on the benzene ring of the MCPs or the aromatic amines can affect significantly the reaction rate.
TsOH/graphite was found to be an effective catalyst system for the Friedel ยฑ Crafts acylation of aromatic compounds with carboxylic acids. Both aliphatic and aromatic carboxylic acids reacted smoothly under TsOH/ graphite catalysis to afford the corresponding aromatic ketones in high yields. The gra