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Mechanism of an in vitro biosynthesis of thyroid hormones from 3,5-diiodo-l-tyrosyl-3,5-diiodo-l-tyrosine

โœ Scribed by Maurizis, J.C.; Michelot, J.; Meyniel, G.


Book ID
122470860
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
348 KB
Volume
540
Category
Article
ISSN
0304-4165

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Mechanism of thyroid hormone biosynthesi
โœ You-An Ma; Charles J. Sih ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 248 KB

Both enzymatic and non-enzymatic oxidative coupling of 3,5-diiodo-L-tyrosine derivatives afforded a T4 derivative and a C3 fragment. The C3 fragment is not dehydroalanine as was claimed by previous workers but rather it was identified as aminomalonic semialdehyde, which decomposed to hydroxypyruvate