Properties and action mechanism of the t
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Olsnes, Sjur ;Sandvig, Kirsten ;Eiklid, Kristin ;Pihl, Alexander
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Article
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1978
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Wiley (John Wiley & Sons)
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English
β 604 KB
The toxic lectin modeccin, which inhibits protein synthesis in eukaryotic cells, is cleaved upon treatment with 2-mercaptoethanol into two peptide chains which move in polyacrylamide gels at rates corresponding to molecular weights 28,000 and 38,000. After reduction, the toxin loses its effect on ce