𝔖 Bobbio Scriptorium
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Studies on the Accessability of Ribosomes to Inactivation by the Toxic Lectins Abrin and Ricin

✍ Scribed by Øystein FODSTAD; Sjur OLSNES

Book ID
115115936
Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
675 KB
Volume
74
Category
Article
ISSN
1432-1327

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✍ Olsnes, Sjur ;Sandvig, Kirsten ;Eiklid, Kristin ;Pihl, Alexander 📂 Article 📅 1978 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 604 KB

The toxic lectin modeccin, which inhibits protein synthesis in eukaryotic cells, is cleaved upon treatment with 2-mercaptoethanol into two peptide chains which move in polyacrylamide gels at rates corresponding to molecular weights 28,000 and 38,000. After reduction, the toxin loses its effect on ce