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Mechanism of action of serine proteases: tetrahedral intermediate and concerted proton transfer

✍ Scribed by Hunkapiller, Michael W.; Forgac, Michael D.; Richards, John H.

Book ID
126298022
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
877 KB
Volume
15
Category
Article
ISSN
0006-2960

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πŸ“œ SIMILAR VOLUMES

Mechanism of serine protease action. Ion
Mechanism of serine protease action. Ionization behavior of tetrahedral adduct between Ξ±-lytic protease and tripeptide aldehyde studied by carbon-13 magnetic resonance
✍ Michael W. Hunkapiller; Stephen H. Smallcombe; John H. Richards πŸ“‚ Article πŸ“… 1975 πŸ› John Wiley and Sons 🌐 English βš– 382 KB

## Abstract Magnetic resonance techniques have been used to study the ionization behavior of the catalytic triad of the serine protease, α‐lytic protease, in the tetrahedral, hemiacetal complex it forms with the aldehyde inhibitor, N‐ac‐L‐ala‐L‐pro‐L‐alaninal. Chemical shift, coupling constant and