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Mechanism of action of FK 506 and cyclosporin

โœ Scribed by Steinmann, Beat; Superti-Furga, Andrea; Bruckner, Peter

Book ID
122495529
Publisher
The Lancet
Year
1991
Tongue
English
Weight
182 KB
Volume
337
Category
Article
ISSN
0140-6736

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Cyclosporin A and FK-506 are important therapeutic agents that have found widespread use in preventing graft rejection during tissue transplantation. Research efforts aimed at elucidating the molecular mechanism of action of these drugs have, in addition to defining their immunosuppressive functions