✦ LIBER ✦

The mechanism of action of cyclosporin A and FK506

✍ Scribed by Stuart L Schreiber; Gerald R Crabtree

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 770 KB
Volume: 13
Category: Article
ISSN: 0167-5699
DOI: 10.1016/0167-5699(92)90111-j

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

FK-506 and cyclosporin A : immunosuppres

FK-506 and cyclosporin A : immunosuppressive mechanism of action and beyond

✍ John J Siekierka; Nolan H Sigal 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 725 KB

Cyclosporin A and FK-506 are important therapeutic agents that have found widespread use in preventing graft rejection during tissue transplantation. Research efforts aimed at elucidating the molecular mechanism of action of these drugs have, in addition to defining their immunosuppressive functions

Studies on mechanisms of augmentation of

Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506

✍ Antonio Francavilla; Thomas E. Starzl; Michele Barone; Qi-Hua Zeng; Kendrick A. 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

Distribution characteristics of immunosu

Distribution characteristics of immunosuppressants FK506 and cyclosporin A in the blood compartment

✍ Kanji Takada; Naohisa Katayama; Akiko Kiriyama; Hisato Usuda 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 781 KB

Using two representative immunosuppressants, FK506 (FK) and cyclosporin A (CyA), of which the mechanism of pharmacological action is the same although there is a great difference in the pharmacological intensity, the distribution characteristics were studied in both in vivo and in vitro experiments

Suppression of B cell activation by cycl

Suppression of B cell activation by cyclosporin A, FK506 and rapamycin

✍ Linda S. Wicker; Robert C. Boltz Jr.; Victoria Matt; Elizabeth A. Nichols; Laure 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 722 KB

## Abstract The effects of the immunosuppressants cyclosporin A (CsA), FK506 and rapamycin have been compared using murine B cells activated with a variety of mitogens. FK506 is a macrolide antibiotic that has been recently shown to inhibit T cell activation by a mechanism that appears similar to t

The immuno-pharmacological outlines of F

The immuno-pharmacological outlines of FK506, 15-deoxyspergualin, mizoribine and cyclosporine

✍ Shiro Takahara; Jiang Hong Si; Masami Machida; Izumi Sakakibara; Hiroshi Amemiya 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 72 KB

Late hypertension after liver transplant

Late hypertension after liver transplantation: A comparison of cyclosporine and tacrolimus (FK 506)

✍ Canzanello, Vincent J. ;Textor, Stephen C. ;Taler, Sandra J. ;Schwartz, Lora L. 📂 Article 📅 1998 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 198 KB

Hypertension frequently develops early after liver transplantation when cyclosporine-based immunosuppression is used. However, initial experience with tacrolimus has suggested that its use leads to a lower early incidence of hypertension. In this study, the blood pressure status of patients treated