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Mechanism of action of carvedilol in human ventricular myocardium

✍ Scribed by Wayne Minobe; Patti Larrabee; Michael R. Bristow

Book ID
119169332
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
194 KB
Volume
17
Category
Article
ISSN
1558-3597

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✍ Bristow, M.R. ;Larrabee, P. ;MοΏ½ller-Beckmann, B. ;Minobe, W. ;Roden, R. ;Skerl, πŸ“‚ Article πŸ“… 1992 πŸ› Springer-Verlag 🌐 English βš– 778 KB

Carvedilol, a new beta-blocker with vasodilating properties due to alpha 1-blockade, was investigated in preparations of human ventricular myocardium. Carvedilol demonstrated a high affinity and is a slightly beta 1-selective competitive beta-blocking agent, with a KD for beta 1-receptors of approxi