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Mechanism for increased bioavailability of tacrine in fasted rats

โœ Scribed by Jong-Hyuk Sung; Soon-Sun Hong; Sung-Hoon Ahn; Hong Li; Seung-Yong Seo; Chul-Hong Park; Byung-Soon Park; Suk-Jae Chung

Book ID
111770533
Publisher
Pharmaceutical Press
Year
2006
Tongue
English
Weight
136 KB
Volume
58
Category
Article
ISSN
2042-7158

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Bioavailability of cyanamide in fasted a
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โœ R. Obach; C. Valenti; J. Valles; J. M. Valles; J. Domenech ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 353 KB ๐Ÿ‘ 1 views

The pharmacokinetics of cyanamide after 35 mg kg-' intravenous and oral administration to fasted and unfasted rats have been investigated. The plasma level are fitted well by a two-compartment open model. The half-life ( t l p) of c anamide in the rat was 1 hour and the plasma clearance (Cl,) was 0.