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Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants

✍ Scribed by Subehan; Tepy Usia; Hiroshi Iwata; Shigetoshi Kadota; Yasuhiro Tezuka


Book ID
116643038
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
337 KB
Volume
105
Category
Article
ISSN
0378-8741

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## Abstract This work presents a method to utilize the ever‐expanding corporate collections of CYP450 inhibition data to forecast the future risk of compounds not yet synthesized. The global/local fusion method differs from existing QSAR methods, in that each prediction is derived from a custom‐bui